A linear B-cell epitope on the class 3 outer-membrane protein of Neisseria meningitidis recognized after vaccination with the Norwegian group B outer-membrane vesicle vaccine
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چکیده
منابع مشابه
Human T-cell responses after vaccination with the Norwegian group B meningococcal outer membrane vesicle vaccine.
We have analyzed human T-cell responses in parallel with serum immunoglobulin G (IgG) antibody levels after systemic vaccination with the Norwegian group B Neisseria meningitidis outer membrane vesicle (OMV) vaccine. Ten adult volunteers, with no or very low levels of serum IgG antibodies against meningococci, received three doses intramuscularly of the OMV vaccine (at weeks 0, 6, and 46). T-ce...
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A novel approach for development of a meningococcal group B vaccine has been developed. This approach , which uses vesicles or blebs of the meningococcal outer membrane prepared without exposure to detergent or denaturing solvents, allows the outer membrane antigens to be presented to the immune system in their natural conformation and membrane environment. Two strategies for using these native...
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The cross-reactivity of PorA-specific antibodies induced by a monovalent P1.7-2,4 (MonoMen) and/or a hexavalent (HexaMen) meningococcal B outer membrane vesicle vaccine (OMV) in toddlers and school children was studied by serum bactericidal assays (SBA). First, isogenic vaccine strains and PorA-identical patient isolates were compared as a target in SBA, to ensure that the vaccine strains are r...
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ژورنال
عنوان ژورنال: Microbiology
سال: 1995
ISSN: 1350-0872,1465-2080
DOI: 10.1099/13500872-141-7-1593